RFamides as Novel Regulators of Reprod...

2012-06-19 神经科学研究中心 浏览量 :   11

RFamides as Novel Regulators of Reproduction and Social Behaviours 

演讲者:PROF ISHWAR PARHAR M.S., Ph.D         
                 MONASH University

DIRECTOR, Brain Research Institute

HEAD of Neuroscience

Jeffrey Cheah School of Medicine and Health Science

Monash University, Sunway Campus, Malaysia

 

Email:ishwar@monsh.edu

SPEAKER PROFILE

Professor  Ishwar  graduated with a M.BMed (Hons) degree from Panjab  University India, Ph.D  from  the  National  University  of  Singapore and a postdoctoral fellowship at the Rockefeller University, New York, USA. Prior to joining Monash University, as Professor and Head of Neuroscience and Founding Director of Brain Research Institute, Professor Ishwar was at Nippon Medical School, Tokyo from 1993-2005. 

ABSTRACT

 

The reproductive neuroendocrine system is controlled by the hypothalamic gonadotropin-releasing hormone (GnRH) neurons. In humans, developmental defects of GnRH neurons results in hypogonadotrophic hypogonadism coupled with anosmia (Kallmann's syndrome). In recent years, the emergence of kisspeptin and gonadotropin-inhibitory hormone have led to a significant revision of our understanding as to how reproductive disorders and social behaviours are controlled by these novel RFamides and their cognate receptors.


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