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Huan Ma's group published in Cell Reports
2021-07-23
The research team led by Prof. Huan Ma has recently published an article titled Neuronal activity recruits the CRTC1/CREB axis to drive transcription-dependent autophagy for maintaining late-phase LTD on Cell Reports online on July 20, 2021 at 11am, ET. Cellular resources must be reorganized for long-term synaptic plasticity during brain information processing, in which coordinated gene transcript...TheresearchteamledbyProf.HuanMahasrecentlypublishedanarticletitledNeuronalactivityrecruitstheCRTC1/CREBaxistodrivetranscription-dependentautophagyformaintaininglate-phaseLTDonCellReportsonlineonJuly20,2021at11am,ET.Cellularresourcesmustbereorganizedforlong-termsynapticplasticityduringbraininformationprocessing,inwhichcoordinatedgenetranscriptionandproteinturnoverarerequired.However,themechanismunderlyingthisprocessremainselusive.Here,wereportthatactivatingNMDARsinducestranscription-dependentauto
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Huan Ma's group published in Neuron
2021-02-06
The research team led by Prof. Huan Ma has recently published an article titled Gating of hippocampal rhythms and memory by synaptic plasticity in inhibitory interneurons on Neuron online on February 5th at 11am, ET. This research uncovered gCaMKII as a mediator of LTPE-I and molecular control of experience-dependent brain rhythms, suggesting that E-I synaptic plasticity plays a gatekeeping r...TheresearchteamledbyProf.HuanMahasrecentlypublishedanarticletitledGatingofhippocampalrhythmsandmemorybysynapticplasticityininhibitoryinterneuronsonNeurononlineonFebruary5that11am,ET.ThisresearchuncoveredgCaMKIIasamediatorofLTPE-Iandmolecularcontrolofexperience-dependentbrainrhythms,suggestingthatE-Isynapticplasticityplaysagatekeepingroleintuningexperience-drivenE-Ispiketransmission,networkactivityandthereforemnemonicfunction.Neuronalactivitytriggeredbyexperiencemodifiesthestrengthofexcitatorysyn
