Seminar: The neuronal mechanism of chronic pain, from synaptic transmission to information coding

 speaker：Xiangyao Li（李相尧）, Ph.D.

                Principal Investigator/Professor

                Lab of Neuronal Circuitry and Disease

                Center for Neuron and Disease

                Frontier Institute of Science and Technology

                Xi'an Jiaotong University

time：10:00-11:00 am ,3rd Dec. (Tuesday), 2013

place：Room B502, research building, school of medicine

contact：Professor Binggui Sun（88981753）

Abstract:

    Chronic pain is a major health issue in human society caused mainly by tissue or nerve injury. The common pathological conditions include spontaneous pain, allodynia and hyperalgesia. Peripheral sensitization and central plasticity are likely to contribute to chronic pain. The long-term change of the synaptic transmission under chronic pain has been studied along the sensory pathway, and PKM zeta has been treated as a new target for chronic pain treatment. And how the enhanced synaptic transmission affects information coding, especially the temporal information coding will be discussed.